PI Akpa and colleagues have been awarded funds to support an interdisciplinary research effort blending systems biology, quantitative genetics, and immunology. (Announcement)
Project title: A systems biology approach to assess host transcriptomics and virus kinetics in reproductive gilts in the face of porcine reproductive and respiratory syndrome.
Lead PIs: Belinda Akpa (CVM) & Nick Serão (CALS)
Co-PIs: Johnathan Fogle, Glen Almond, Mark Knaeur
Our thanks to the College of Agriculture and Life Sciences and the College of Veterinary Medicine for their support!
An article by Dr Akpa and colleagues in the Department of Anesthesiology has been the subject of an upcoming editorial in the journal Anesthesiology. Dr. Geoffrey Tucker writes that the combination of complex small animal experiments and physiological modeling reported:
“… should be applauded as a creative modeling exercise resulting in significant gain in insight into the mechanisms of lipid resuscitation which opens the way for further investigation of the optimal clinical implementation …”
See the rest of the editorial here and see our paper here.
A little oil in your veins could prevent loss-of-life. As the rate of death due to unintentional poisoning outstrips that associated with motor vehicle accidents, the need for efficient antidotes is increasingly urgent. Our lab is working to accelerate the development of a potential broad-spectrum antidote by implementing mathematical models at molecular and organism scales and integrating these with the experimental findings of physician-scientists.
NSF Grant 1228035
PI Douglas Feinstein is leading this effort to assess lipid emulsions as a countermeasure against superwarfarin poisonings. The project brings together investigators in Medicine, Engineering, and Pharmacy at UIC. More information.
NIH CounterACT grant 1U01NS083457.