Research Interests

 Quantitative, multi-scale modeling to determine the rules underlying phenotype variations from scarce, qualitative, and heterogeneous data 

⇒ We build mathematical models to provide quantitative conceptual frameworks that are…

⇒ Informed by basic science questions and translational challenges in biology with the aim of using these models to…

⇒ Inform further experimental interrogation of both the individual and collective behaviors of key players in important physiological processes

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Activities by topic

regulation of membrane fusion, regulation of ion channel function by membrane lipids, computational forensics, stem cell signaling

Activities by approach/method

molecular dynamics simulation, intra-cellular signaling pathways, network theory, Bayesian inference, hidden Markov models, physiologically-based pharmacokinetic-pharmacodynamic models, machine learning, rule-based modeling

NEWS