Category Archives: News

Welcoming the new year with a new publication in Biophysical Journal!

Ayee-biophysj2017Congrats to Manuela Ayee on her first author publication in Biophysical Journal! This collaborative effort with the Levitan group employs experimental biophysical and biochemical tools, along with molecular modeling, to explore the influence of oxidized lipid species on membrane structure and the apparent inverse relationship between the mechanics of the lipid bilayer and those of the endothelial cell.

Molecular-Scale Biophysical Modulation of an Endothelial Membrane by Oxidized Phospholipids

Highlighted in a New & Notable feature

Undergrad researcher Nicholas Biondo to present at NC Undergraduate Research and Creativity Symposium

Saturday, Nov 5 will find Animal Science junior Nick Biondo presenting a poster on his molecular simulations at SNCURCS 2016. Nick’s poster, entitled ‘Is lipophilicity a valid predictor of drug sequestration? An investigation in support of lipid resuscitation‘ will be on display from 9:45 to 10:45AM.  Congrats from EMRLab to our first pre-VetMed lab member!

Flores Lab student Matthew McDaniel to present at AAPS

If you happen to be at the American Association of Pharmaceutical Scientists meeting next month, stop by and see Matt McDaniel presenting his poster on Monday, Nov 14 at 3PM.  His work details our collaborative use of mathematical models to explore responses to lipid emulsion therapy following local anesthetic toxicity in a virtual population.

Parameter Estimation on a Physiologically Based PK/PD Model for Dose-Dependent Intravenous Lipid Emulsion Therapy in Rats

Matthew McDaniel, Kevin Flores, Belinda Akpa

Synthetic and Systems Biology Discussion Group kicks off at NC State

Starting on Friday, Sept 2 and monthly on the first Friday of each month, the Synthetic and Systems Biology (SyntheSys) cluster at NC State will be hosting a discussion series to foster cross-campus interactions and collaborations.

Meetings: first Friday of every month in David Clark Labs 101. Howling Cow ice cream, coffee, and socializing will begin at 3:30pm, and discussion session will run from 4-5pm.

The group’s goals are to:

  1. Help students, postdocs, and faculty efficiently learn about relevant methodologies (“Hammers”) and biological questions (“Nails”).
  2. Promote collaborations and identify unexpected synergies.

Each session will focus on a specific theme with a highly interactive format of:

  1. A “Hammer talk”: 15 minute talk about a method (detailed background and identification of strengths and limitations)
  2. A “Nail talk”: 15 minute talk on a related “Nail” (i.e., biological question)

Speakers will focus on informative background material, current hurdles, and ambitious ideas. Each speaker will be followed by a 10-minute discussion period to permit Q&A and idea-generation. We will close with a final 10-minutes for open exchange.